Spray-dryer feed preparation: Enzymatic degradation of glucomannan for iron nanoencapsulation

<abstract> <p>Viscosity of glucomannan (GM) needs to be modified support its application for spray drying encapsulation. The purpose this study was investigate degradation GM using cellulase that fulfills viscosity in a spray-dryer specification. This hydrolyzed (HGM) subsequently spray-dried encapsulating iron. Lower initial concentrations (0.5–1%) reached approximately 0.30 Pa·s which allowed after 100 min 10 mg/L cellulase. Meanwhile, 1.5% and 1.7% did not reach the target even 300 min. n<sup>th</sup>-order model most suitable fitted reduction ≤1.5% concentration (coefficient determination, R<sup>2</sup> > 0.98), whereas Mahammad 1.75% (R<sup>2</sup> = 0.99). Hydrolysis decreased degree polymerization surface tension but increased antioxidant activities HGM. Smaller molecules polysaccharides were released hydrolysis. Particles encapsulated iron HGM more hydrophilic than those GM. tended have higher release rate at pH 6.8 1.2 first 40 Hence, showed ability act as control matrix protection acid environment, delivers them neutral site absorption. Nanoencapsulation 0.35 able 84% yield, 96.41% encapsulation efficiency, 10% moisture content. Particle size dominated by 341.99 nm-diameter. shows potency use an appropriate only allows also protecting aimed Performances properties on other bioactive compounds become future study.</p> </abstract>